Atorvastatin 40 mg


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Atorvastatin

(Blood lipid-lowering drugs -tablets)

medicine name: Atorvastatin

Drug category: Statins, lipid-lowering drugs

Indications:

Atorvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Atorvastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.

Mechanism of action:

It inhibits the enzyme HMG-CoA reductase in the liver, which plays a key role in cholesterol biosynthesis.

Pharmacokinetics:

It has a half-life of 14 hours, after absorption in the gastrointestinal tract, is metabolized by the liver and excreted in the feces.

The correct amount and method of consumption:

adults:

In the prevention of cardiovascular disease, 10 mg should be taken once a day.

In familial and non-familial hypercholesterolemia, heterozygous and mixed dyslipidemia: initial dose 10 to 20 mg daily, then maintenance dose 10 to 80 mg daily.

For patients who need a large reduction in LDL (more than 45%) should start with an initial dose of 40 mg daily.

Lipid levels should be analyzed every 2 to 4 weeks after starting the drug, then the dose of the drug should be adjusted.

In homozygous familial hypercholesterolemia: dose 10 to 80 mg

children:

Heterozygous familial hypercholesterolemia in children 10 to 17 years: 10 mg daily, dose adjustment is done by checking lipid levels every 4 weeks.

Contraindication:

If you are allergic to this drug, do not use it.

Warning:

Consult your doctor or pharmacist if you have liver failure, alcohol consumption, myopathy or seizures.

You should not use atorvastatin if you are allergic to it, or if you have: liver disease; or if you are pregnant or breastfeeding.

Stop taking this medication and tell your doctor right away if you become pregnant.

Drug interactions:

Concomitant use of this drug interferes with cyclosporine, fibrosil jam and ketoconazole.

side effects:

All medications, along with the desired therapeutic effects, may cause some side effects, although not all side effects can be seen in one person, but consult your doctor if any of the following side effects occur.

Gastrointestinal upset such as diarrhea and abdominal pain

Pregnancy and lactation:

The Food and Drug Administration (FDA) in the United States has designated all statins (e.g. Atorvastatin) category X, which means their use during pregnancy is contraindicated.

Storage:

Keep the tablets away from light, moisture and at a temperature below 30 ° C.

Keep the tablets in the box until used.

Keep out of the reach of children.

Product shape and packaging:

Atorvastatin 10, 20 and 40 mg tablets are supplied in boxes of 30.

Manufacturer:

Daana Pharma Co.